PKUMDL-WQ-2101
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Total: $0.00
$0.00
| Unit | Price | Qty |
|---|---|---|
| 5 mg | $48.40 |
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| 10 mg | $77.00 |
|
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Novel selective allosteric inhibitor of PHGDH and serine synthesis with anti-tumor activity, binding to site I
| Technical Data | |
| Chemical Formula | C14H11N3O6 |
| CAS Number | 304481-72-9 (2095878-12-7) |
| Molecular Weight | 317.25 |
| Solubility | Soluble to 100 mM in DMSO |
| IUPAC/Chemical Name | (E)-2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide |
| Purity | 98% by HPLC |
| Storage | 0°C (short term), -20°C (long term), desiccated |
| InChI Key | OXONIXZPWKJHMW-VIZOYTHASA-N |
| InChl Code | InChI=1S/C14H11N3O6/c18-10-2-3-11(13(20)6-10)14(21)16-15-7-8-5-9(17(22)23)1-4-12(8)19/h1-7,18-20H,(H,16,21)/b15-7+ |
| Smiles | O=C(N/N=C/C1=CC([N+]([O-])=O)=CC=C1O)C2=CC=C(O)C=C2O |
| References | Wang et al (2017) Rational design of selective allosteric inhibitors of PHGDH and serine synthesis with anti-tumor activity. Cell Chem.Biol. 24 55 PMID |
| Synonym | PKUMDL WQ 2101 |